Well Ruby Tuesday's restaurant, and now building are history in Florence. Come Friday, May 5th, 2017 the building will be destroyed and removed from the property to make way for a new restaurant, at least that's what I have heard from some of the workers at the site.
Although they couldn't tell me the name of the new restaurant they did say that it was going to be a Chinese restaurant. Given the area and looking around at what's not here it's very possible that it might be a Panda Express but then who knows? It could be anything.